A Dra. Catherine Bourgouin, pesquisadora do Mosquito-Plasmodium Interaction Research Group, no Institut Pasteur/França, está em busca de um pós-doc jovem ou sênior, com experiência em biologia molecular e bioinformática, para assumir parte de seus projetos como grupo de pesquisa independente no futuro. Isso se encaixará com a criação de um departamento de doenças transmitidas por vetores que será desenvolvido no Instituto Pasteur, na estrutura de um edifício totalmente novo, dedicado principalmente à biologia vetorial, que está planejado para ser inaugurado em 2025.
Veja abaixo a descrição dos dois projetos de pesquisa desenvolvidos pela Dra. Catherine e algumas oportunidades para se obter o financiamento da bolsa Pos-doc:
The first project* is aimed at investigating the molecular basis of a mosquito maternal effect that drives differential susceptibili to Plasmodium falciparum of the mosquito offspring. Details supporting this biological feature can be found in the following preprint : https://www.biorxiv.org/content/10.1101/2020.01.27.922070v1
This project will use diverse approaches, notably epigenetic tools (ie-ATAQ-seq) and bio-informatics as well as metabolomics and mosquito infection with P. falciparum. It will be done in collaboration with Christophe Antoniewski, head of the ARTBio bioinformatic platform (Sorbonne University) and specialist in Drosophila epigenetics.
The second project is centered on functional analysis of genes identified through a differential proteo-transcriptomic analysis of Anopheles arabiensis infected with either P. falciparum or Plasmodium vivax (publication in prep). Mosquitoes were initially infected in a field station in Madagascar. While my group has a long-standing expertise in mosquito lab infection with P. falciparum, mosquito infection with P. vivax needs to be established in the lab. To this aim, a collaborative project involving Didier Ménard and collaborators from Madagascar has been set up.
The Institut Pasteur is a great scientific and international environment with access to multiple facilities including genomics, proteomics, bio-informatics and imaging. Interactions with the Institut Pasteur International Network (IPIN or RIIP, in French) is also of additional interest when working on malaria transmission.
Opportunities to apply for postdoc funding :
• Pasteur-Roux-Cantarini Postdoctoral Fellowships –Fall 2020 call. Application deadline: September 15, 2020(https://research.pasteur.fr/en/call/pasteur-roux-cantarini-postdoctoral-fellowships-fall-call-2020/).
A spring call will be launch early 2021
• European MSCA-IF-2020: Individual Fellowships (https://ec.europa.eu/research/participants/data/ref/h2020/wp/2018-2020/main/h2020-wp1820-msca_en.pdf) deadline September 9th 2020
• EMBO postdoctoral fellowship (https://www.embo.org/funding-awards/fellowships/postdoctoral-fellowships.html#benefits) next deadline : Feb 12th 2021
*Dra. Catherine is expecting a specific postdoc funding associated with the first project (grant pending).
